Top 25 Deals On South America Cruises

Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Saturday, Feb 14th 2026
Returning: Barranquilla, Colombia
Saturday, Feb 21st 2026
Balcony From: $3860pp
$350 Bonus Onboard Credit!
Suite From: $5759pp
$600 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Barranquilla, Colombia
Wednesday, Dec 24th 2025
Returning: Cartagena, Colombia
Wednesday, Dec 31st 2025
Balcony From: $3850pp
$350 Bonus Onboard Credit!
Suite From: $5274pp
$500 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_xmas.png  Cruise on Christmas!
va_newyear.png  Ring in the New Year on this Cruise!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  Costa Cruises
Ship:  Costa Deliziosa
Destination:  South America
Departing: San Antonio, Chile
Sunday, Jan 19th 2025
Returning: Sydney, Australia
Saturday, Feb 22nd 2025
Inside From: $5601pp
Outside From: $6241pp
Balcony From: $7201pp
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_mlk.png  Cruise on Martin Luther King Jr. Day!
va_presidents.png  Cruise on President’s Day!
Cruiseline:  MSC Cruises
Ship:  MSC Grandiosa
Destination:  South America
Departing: Maceio, Brazil
Wednesday, Feb 12th 2025
Returning: Maceio, Brazil
Wednesday, Feb 19th 2025
Inside From: $683pp
$50 Bonus Onboard Credit!
Outside From: $833pp
$75 Bonus Onboard Credit!
Balcony From: $993pp
$150 Bonus Onboard Credit!
Suite From: $1993pp
$400 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Cartagena, Colombia
Wednesday, Aug 27th 2025
Returning: Barranquilla, Colombia
Wednesday, Sep 3rd 2025
Balcony From: $3755pp
$350 Bonus Onboard Credit!
Suite From: $5179pp
$500 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Saturday, Aug 30th 2025
Returning: Barranquilla, Colombia
Saturday, Sep 6th 2025
Balcony From: $3689pp
$350 Bonus Onboard Credit!
Suite From: $5688pp
$550 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  MSC Cruises
Ship:  MSC Grandiosa
Destination:  South America
Departing: Salvador, Brazil
Tuesday, Feb 11th 2025
Returning: Salvador, Brazil
Tuesday, Feb 18th 2025
Inside From: $708pp
$50 Bonus Onboard Credit!
Outside From: $858pp
$75 Bonus Onboard Credit!
Balcony From: $1018pp
$150 Bonus Onboard Credit!
Suite From: $2868pp
$650 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Barranquilla, Colombia
Wednesday, Sep 2nd 2026
Returning: Cartagena, Colombia
Wednesday, Sep 9th 2026
Balcony From: $3955pp
$400 Bonus Onboard Credit!
Suite From: $5474pp
$550 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Barranquilla, Colombia
Saturday, Sep 5th 2026
Returning: Cartagena, Colombia
Saturday, Sep 12th 2026
Balcony From: $3955pp
$400 Bonus Onboard Credit!
Suite From: $5854pp
$600 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Saturday, Jul 4th 2026
Returning: Barranquilla, Colombia
Saturday, Jul 11th 2026
Balcony From: $3955pp
$400 Bonus Onboard Credit!
Suite From: $5854pp
$600 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_flag.png  Cruise on the 4th of July!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  Windstar
Ship:  Star Pride
Destination:  South America
Departing: Lima, Peru
Thursday, Jan 29th 2026
Returning: Puntarenas / Puerta Caldera, Costa Rica
Monday, Feb 16th 2026
Suite From: $6794pp
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
call.png  Call for a Discounted Quote!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Thursday, Feb 12th 2026
Returning: Barranquilla, Colombia
Saturday, Feb 21st 2026
Balcony From: $4850pp
$500 Bonus Onboard Credit!
Suite From: $6749pp
$700 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  Princess
Ship:  Sapphire Princess
Destination:  South America
Departing: Buenos Aires, Argentina
Friday, Feb 7th 2025
Returning: Santiago, Chile
Friday, Feb 21st 2025
Inside From: $2178pp
$50 Bonus Onboard Credit!
Outside From: $2273pp
$100 Bonus Onboard Credit!
Balcony From: $4428pp
$450 Bonus Onboard Credit!
Suite From: $3714pp
$400 Bonus Onboard Credit!
Special Offers Available On This Sailing:
https://booking.sigtn.com/site/images/promotions/ICONS_Main_16_PCL%20PLUS.png  Princess Plus Fares: Includes Princess Plus Beverage Package, Wi-Fi, Crew Appreciation & More! (Click for terms.)
https://booking.sigtn.com/site/images/promotions/ICONS_Main_17_PCL%20PREMIER.png  Princess Premier Fares: Includes Princess Premier Beverage Package, Multi-Device Wi-Fi, Specialty Dining, Crew Tips, Photo Package & More! (Click for terms.)
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
bpcobc.png  Onboard Credit! (Applies to All Categories - Value in Cruise Cash)
Cruiseline:  MSC Cruises
Ship:  MSC Poesia
Destination:  South America
Departing: Buenos Aires, Argentina
Tuesday, Feb 11th 2025
Returning: Buenos Aires, Argentina
Thursday, Feb 20th 2025
Balcony From: $1567pp
$250 Bonus Onboard Credit!
Suite From: $2547pp
$500 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
Cruiseline:  Silversea
Ship:  Silver Ray
Destination:  South America
Departing: Ft Lauderdale, Florida
Thursday, Dec 19th 2024
Returning: Callao, Peru
Saturday, Jan 4th 2025
Suite From: $5500pp
$500 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_xmas.png  Cruise on Christmas!
va_newyear.png  Ring in the New Year on this Cruise!
va_hanukkah.png  Cruise during Hanukkah!
Cruiseline:  MSC Cruises
Ship:  MSC Poesia
Destination:  South America
Departing: Montevideo, Uruguay
Wednesday, Feb 12th 2025
Returning: Montevideo, Uruguay
Friday, Feb 21st 2025
Inside From: $1178pp
$100 Bonus Onboard Credit!
Outside From: $1298pp
$100 Bonus Onboard Credit!
Balcony From: $1498pp
$200 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_heart.png  Cruise on Valentine’s Day!
va_presidents.png  Cruise on President’s Day!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Cartagena, Colombia
Wednesday, Jun 18th 2025
Returning: Barranquilla, Colombia
Wednesday, Jun 25th 2025
Balcony From: $3689pp
$350 Bonus Onboard Credit!
Suite From: $5188pp
$500 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_juneteenth.png  Cruise on Juneteenth!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  Lindblad Expeditions
Ship:  NG Orion
Destination:  South America
Departing: Santiago, Chile
Monday, Feb 15th 2027
Returning: Ushuaia, Argentina
Wednesday, Feb 24th 2027
Outside From: $13786pp
Suite From: $16095pp
Special Offers Available On This Sailing:
va_presidents.png  Cruise on President’s Day!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Cartagena, Colombia
Monday, Aug 25th 2025
Returning: Barranquilla, Colombia
Wednesday, Sep 3rd 2025
Balcony From: $4655pp
$450 Bonus Onboard Credit!
Suite From: $6079pp
$600 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  Norwegian Cruise Line
Ship:  Norwegian Star
Destination:  South America
Departing: Buenos Aires, Argentina
Sunday, Feb 16th 2025
Returning: Ushuaia, Argentina
Saturday, Mar 1st 2025
Inside From: $1821pp
$50 Bonus Onboard Credit!
Outside From: $2071pp
$100 Bonus Onboard Credit!
Balcony From: $2941pp
$225 Bonus Onboard Credit!
Suite From: $3441pp
$425 Bonus Onboard Credit!
Special Offers Available On This Sailing:
https://booking.sigtn.com/site/images/promotions/ICONS_22_Airplane.png  Ask About Potential Air Savings. AIR MUST BE BOOKED DIRECTLY WITH NORWEGIAN. Click for terms.
https://booking.sigtn.com/site/images/promotions/ICONS_Main_31_Free_at_Sea.png  Receive Up to Five "Free at Sea" Perks in Select Staterooms with Select Fares. Choose from Beverage Package, Dining Package, Internet Package, Shore Excursion Credit, and More!. Perks vary by fare/promo code selected. Gratuities fees may apply* (Clic
va_presidents.png  Cruise on President’s Day!
bpcobc.png  Onboard Credit! (Applies to All Categories - Value in Cruise Cash)
https://book.bestpricecruises.com/site/images/promotions/va_freetips.png  Exclusive: Receive Free Pre-Paid Gratuities When You Book A Balcony or Above!
Cruiseline:  Oceania Cruises
Ship:  Vista
Destination:  South America
Departing: San Diego, California
Saturday, Mar 7th 2026
Returning: Miami, Florida
Monday, Jul 6th 2026
Balcony From: $50149pp
$5000 Bonus Onboard Credit!
Special Offers Available On This Sailing:
https://booking.sigtn.com/site/images/promotions/simplymore%20png.png  simplyMORE Fares: 2 for 1 Cruise Fares, Shore Excursion Credit, Beverage Package, Specialty Dining & WiFi. Ask About Air Savings. (Click for terms.)
https://book.bestpricecruises.com/site/images/promotions/va_summer.png  ANNUAL SUMMER SALE: Up to 40% Off on Select Sailings!
va_flag.png  Cruise on the 4th of July!
va_easter.png  Cruise on Easter!
memorial.png  Cruise on Memorial Day!
va_juneteenth.png  Cruise on Juneteenth!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Barranquilla, Colombia
Wednesday, Apr 1st 2026
Returning: Cartagena, Colombia
Wednesday, Apr 8th 2026
Balcony From: $3860pp
$350 Bonus Onboard Credit!
Suite From: $5379pp
$550 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_easter.png  Cruise on Easter!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMelodia
Destination:  South America
Departing: Cartagena, Colombia
Wednesday, May 20th 2026
Returning: Barranquilla, Colombia
Wednesday, May 27th 2026
Balcony From: $3860pp
$350 Bonus Onboard Credit!
Suite From: $5379pp
$550 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
memorial.png  Cruise on Memorial Day!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Thursday, Jul 3rd 2025
Returning: Barranquilla, Colombia
Saturday, Jul 12th 2025
Balcony From: $4589pp
$450 Bonus Onboard Credit!
Suite From: $6588pp
$650 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_flag.png  Cruise on the 4th of July!
va_hotdeal.png  Exclusive Bonus Discount!
Cruiseline:  AmaWaterways
Ship:  AmaMagdalena
Destination:  South America
Departing: Cartagena, Colombia
Thursday, Aug 28th 2025
Returning: Barranquilla, Colombia
Saturday, Sep 6th 2025
Balcony From: $4589pp
$450 Bonus Onboard Credit!
Suite From: $6588pp
$650 Bonus Onboard Credit!
Special Offers Available On This Sailing:
va_wifi.png  Free Wifi Onboard!
va_anchor.png  Shore Excursions Included!
va_drink.png  Complimentary Drinks & Bottled Water Included!
https://book.bestpricecruises.com/site/images/promotions/va_sale.png  Agency Exclusive Promotion! - $100 Per Person Discount!
va_redwhiteblue.png  Cruise on Labor Day!
va_hotdeal.png  Exclusive Bonus Discount!

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Royal Caribbean Kids Sail Free Super Sale!

Take a Cruise and Bring the Kids with Royal Caribbeans Kids Sail Free Offer! Plus Get Our Bets Price Cruises Exclusives!

MSC Cruises Hot Sale!

Get Ultra Low Rates on Your Next Close-to-Home Cruise! Plus, Exclusive Onboard Credit from Best Price Cruises!

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Get our Best Price Cruises exclusive free prepaid gratuities and onboard credit! Plus get 70% off your 2nd guest and up to 5 free perks from Norwegian!

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Check Out Our Last Minute 2024 Princess deals with Exclusive $100 Minimum Cruise Cash from Best Price Cruises!

Royal Caribbean Get Your Cruise on Offer!

Get big savings, 60% off your second guest and kids sail free! Plus get our Best Price Cruises exclusive onboard credit!

Find Your Next Japan Cruise

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Our Most Popular AmaWaterways Cruises

  • Outsides from $4930
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  • Insides from $651
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